miREX

Publications

Przanowski P, Wasko U, Zheng Z, Yu J, Sherman R, Zhu LJ, McConnell MJ, Tushir-Singh J, Green MR, Bhatnagar S. Pharmacological reactivation of inactive X-linked Mecp2 in cerebral cortical neurons of living mice. Proceedings of the National Academy of Sciences of the USA, 2018.

Posters & Presentations

Powers S*, Lou S, Nardini S, Likhite S, Sierra-Delgado JA, Baird M, Roussel F, Kaleem A, Schwartz M, Ray S, Bhatnagar S, Meyer K. A novel gene therapy for Rett Syndrome through reactivation of the silent X chromosome. Presented at the 25th American Society of Gene and Cell Therapy (ASGCT) Annual Meeting, 2022. *Received Excellence in Research Award

Relevant Scientific Publications

Grimm, NB, Lee, JT. Selective Xi reactivation and alternative methods to restore MECP2 function in Rett syndrome. Trends in Genetics, 2022.

Vacca M, Della Ragione F, Scalabrì F, D'Esposito M. X inactivation and reactivation in X-linked diseases. Seminars in Cell and Developmental Biology, 2016.