Science & Technology

Intra-CSF Drug & Delivery Optimization

Dosing & delivering gene-based therapeutics to the brain with efficiency and precision is critical for successful treatment of complex neurological conditions, and a challenge that has been nearly insurmountable – until now. Introducing Falcon™, Alcyone’s novel precision intra-CSF (cerebrospinal fluid) drug and delivery platform technology.

Industry standard approaches to targeting the nervous system, such as bolus delivery to the lumbar spine, facilitate minimal brain penetration and cellular targeting, with inconsistent results that lead to poor therapeutic success. Furthermore, it is also important to optimize drug and buffer properties that allow for desired transport in the CSF. Falcon™ allows for targeted and efficient intra-CSF dosing of medications to neural tissues by the combination of state-of-the-art delivery technology with one-of-a-kind computational algorithms to optimize drug properties and delivery parameters based on desired target region(s), cerebrospinal fluid (CSF) dynamics and unique patient physiological characteristics.